Feed-grade Zinc Oxide ZnO Used to Control Diarrhea in Piglets
Recently, the EU proclaimed new sanctions on Russia, including coal, timber, rubber, cement, and fertilizer, as well as high-end seafood zinc oxide.
Zinc oxide is an oxide of zinc. Insoluble in water, soluble in acids and strong bases. Zinc oxide is mainly used in chemical industry, pharmaceutical industry, agriculture and other fields.
Feed-grade zinc oxide has a significant effect on the safe control of piglet diarrhea. However, zinc oxide will also cause rough coat of piglets, unbalanced absorption of trace elements, late growth retardation, environmental pollution and other problems. Therefore, feed-grade zinc oxide is a double-edged sword in controlling diarrhea in piglets.
Zinc oxide does have a good effect on controlling diarrhea. But zinc oxide as an amphoteric oxide, first of all, more than 70% of zinc oxide in gastric acid can not pass safely in the form of functional molecular state ZnO, and is transformed into Zn2+ which has no diarrhea control effect. Not to mention the destruction of bile and small intestinal fluid in the intestine. This is an important reason why a large amount of zinc oxide must be added to ensure that enough ZnO reaches the intestinal tract to play a role and achieve a good diarrhea control effect. For those dissolved Zn2+, will be over-absorbed, high blood zinc concentration, resulting in adverse effects on piglet coat color, growth speed and immune function.
So how to maximize the efficacy of zinc oxide, let the zinc of 1500ppm (based on zinc) play the role and effect of 3000ppm under conventional conditions, so that zinc oxide is not destroyed by digestive juices such as gastric acid, and exists and evenly dispersed in the intestinal tract in the form of molecular ZnO in its effective form?
How to deal with it?
Acid resistance, compatibility with chyme and lipophilicity are the decisive factors that determine whether zinc oxide can maximize the effect of antidiarrheal convergence. Only when zinc oxide is acid-resistant, can it not be neutralized by gastric acid, and can it reach the intestinal tract with molecular zinc oxide particles that can control diarrhea; only when zinc oxide is compatible with chyme can it be rapidly and uniformly dispersed in the intestinal tract and form a uniform protective film on the surface of the entire intestinal mucosa; only when zinc oxide is lipophilic, it can be in close contact with the intestinal mucosa of lipids and enrich to the surface of the intestinal mucosa, and the effect will be better.
How to treat zinc oxide with acid resistance? How to make zinc oxide disperse evenly in the intestines? How to make zinc oxide in close contact with intestinal mucosa? It is a problem that the manufacturer needs to solve.
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Gas prices in European countries are expected to triple if Russian supplies are restricted, according to a press release from Rystad Energy, a Norwegian Energy consultancy.
The price of natural gas in Europe was $1,200 per 1,000 cubic meters on Tuesday. The benchmark price is already 300 percent higher than a year ago. European gas prices are expected to continue to soar to $3,500 per 1,000 cubic meters if Russian supplies are restricted, according to Analysis by Monitor.
In 2021, Russia delivered 155 billion cubic meters of gas to Europe, accounting for 31 percent of its gas supply, according to an analysis by Monitor Advisors. It would be difficult for Europe to replace Russian gas, which would also destabilize the global LNG market and have a profound impact on Europe's population and economy.
The analysis also said that if Russia stopped supplies now, Europe's current gas reserves would be exhausted by the end of the year, setting in for a cold winter.
In addition, affected by the geopolitical factors, the supply of the zinc oxide is erratic and thus its prices are expected to go higher in the future.